Activation mechanisms of adherent human neutrophils

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Activation mechanisms of adherent human neutrophils.

The mechanism by which unstimulated human neutrophils initiate a respiratory burst on adherence to a surface has been examined. When neutrophils adhere to a plastic surface, they immediately generate a sustained burst of superoxide (O2-). However, this respiratory burst is not initiated by adherence alone, since neutrophils attached to fibronectin fail to mount a response. Adhesion to plastic i...

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ژورنال

عنوان ژورنال: Blood

سال: 1990

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v76.6.1233.bloodjournal7661233